Understanding Flow Chemistry
Flow microchemistry or plugs flows are other names that refer to Flow chemistry. A chemical reaction run in a pipe or a tube is known as a flow chemistry The process involves pumping reactive components together at a mixing junction and then following down a temperature controlled pipe or a tube. The fluids in a pipe or a tube are moved in the pumps and where the tubes join one another fluids get into contact with each other. A flow reactor is where the flow chemistry is achieved, and thus chemical reactions take place in micro channels. Flow chemistry is effectively and largely used in large manufacturing companies.
Some of the major advantages of flow chemistry are that it offers faster reactions. Flow reactions can be easily pressurized by a process called super-heating thus allowing reactions to be heated 100 to 150 degrees above normal boiling points thus creating reactions rates that are 1000 times faster. Secondly cleaner products are achieved by when flow reactors enable excellent reaction selectivity. Rapid diffusion mixing increase the surface area to volume ratio thus enabling instantaneous heating or cooling, therefore, offering ultimate temperature control. Flow chemistry allows only a small amount of hazardous intermediate to be formed at any instant thus allowing excellent control of exotherms. flow will focus on concentration of flow reagents and their ratio of their flow rate, unlike batch which focuses on the concentration of chemical reagents and their volumetric ratio.
Reaction products can be analyzed in line or by sampler or diluter since they exist in a flow reactor and can be flowed into an aqueous flow work up a system. Automation will allow plug flows to offer Rapid reaction optimization by enabling quick variations of reactions conditions on a microscopic scale. Scale up issues is also minimized due to maintaining excellent mixing and heat transfer. Flow chemistry such as a five-second reaction at 250 degrees are enabled but are not possible in batch . Rapid, low temperature deprotonation followed by instant addition of electrophile high temperatures is made possible in multistep procedure.
Syrris is one of the largest examples of flow chemistry.Spinning disk reactors, spinning tube reactors, multicell flow reactors and oscillator reactors are other types of flow chemistry recators Variety of flow chemistry notes and reactions using flow chemistry systems are demonstrated by range of resources in syrris. Among the drawbacks of flow chemistry is that it will require a dedicated equipment for precious continuous dosing. For the flow chemistry to be effective, the startup and shut up time of the process must be established.